NEWSLETTER: https://tinahuang.substack.com/ It's about learning, coding, and generally how to get your sh*t together c: I've been a FAANG data scientist f. 5). Publication: Huang T, Reimand J. Network-rewiring mutation in kinase signaling networks are informative of cancer patient. This free online conference is featuring panel discussions from In the video above, she explains the two major components of big data: data warehousing and data science. and J.Krause performed or supervised genetic analyses. Hi! Natl Acad. The more information you have the more data you need to analyze and make your predictions. Early Alpine occupation backdates westward human migration in Late Glacial Europe. This article reviews qualitative and quantitative studies related to the academic achievement of youth from immigrant Chinese families. This suggests that the newly reported Neolithic individual from central Asia carries an ancestry that might be a good proxy for the ANE-related contribution to Iran and the Turan region45 from around 5.5ka but not to roughly contemporaneous hunter-gatherers from eastern Europe. The Kostenki genetic signature (related to the Kostenki 14 genome, and hereafter referred to as the Kostenkicluster or ancestry) contributed to the later Vstonice genetic cluster(hereafter,Vstonice cluster or ancestry), named after the Doln Vstonice site in Czechia4. The y axis shows the average of calibrated radiocarbon dates in thousands of years (kyr) (Supplementary Data 1.A). 26, 827833 (2016). Designed for aspiring data scientists, data analysts, and BI analysts, this course is the perfect resource for anyone who needs a winning strategy to pass the SQL interview and land their dream job. The LGM could thus have created a corridor south of the Alps for east-to-west human movements that genetically connected hunter-gatherer populations from the Balkans to Iberia, possibly also via dispersals along existing lower-sea-level coasts32. PubMed In this debated framework, Gravettian-associated individuals have been suggested to represent a biologically homogeneous population on the basis of craniometric and genomic data4,22. 1 MtDNA and Y-chromosome phylogenies. You'll likely won't meet her on a day to day basis, but she's always lurking in the Discord and following everybody's progress (not . The MySQL engine is also known for being extremely slow compared to others. Tina Huang - Instructor | 365 Data Science Contact Us. Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. Details are provided in Data S2.B. Olalde, I. et al. Tina Huang - Data Scientist - Children's Hospital Los Angeles (CHLA Hollywood Heights. The dimensions are calculated using newly reported and previously published hunter-gatherer groups or individuals with more than 30,000 SNPs. Tina is a data scientist working in tech and does Youtube part time. Note: Content may be edited for style and length. 12, 5425 (2021). Int. Genetic ancestry changes in Stone to Bronze Age transition in the East European plain. 6 and Supplementary Fig. 3). The phylogenetic reconstruction of Epigravettian-associated genomes, with Pradis 1 diverging more deeply than all others, indicates that the turnover took place much earlier than 17kathe date of the more derived Tagliente 2 genome. Created by DataSciencePR. TV Actresses. She majored in mathematics before switching to computer science. These data cover a time span of around 30,000 years from the Upper Palaeolithic to the Late Neolithic (defined here by the presence of pottery rather than by farming subsistence economy if not indicated), derive from multiple prehistoric cultural contexts, and originate from 54 archaeological sites in 14 countries: 1 Aurignacian-associated individual from Belgium and 1 culturally unassigned individual from Romania (3533ka), 15 Gravettian-associated individuals from Spain, France, Belgium, Czechia and Italy (3126ka), 2 Solutrean-associated individuals from Spain and France (2321ka), 9 Magdalenian-associated individuals from France, Germany, and Poland (1815ka), 4 Epigravettian-associated individuals from Italy (1713ka), 2 Federmesser-associated individuals from Germany (14ka), and 81 Mesolithic to Neolithic foragers from across western Eurasia (115ka), together with 1 central Eurasian Neolithic individual from Tajikistan (8ka) (Fig. We use cookies to improve your experience and give you personalized content. 41 Year Olds. Protoc. Extended Data Fig. Inconsistent haplogroup assignments were manually verified as indicated24 (Supplementary Data 1.L). What is Connection Map in Data Visualization? This is also supported by f4-statistics of the form f4(Mbuti, Fournol 85; Sunghir, test), which are significantly positive for all the individuals included in the Vstonice cluster (Supplementary Data 2.B). Google Scholar. These f4-statistics also confirm that Goyet Q376-3 carries a similar ancestry to Goyet Q116-1 and Kostenki 12 carries a similar ancestry to the Sunghir group, whereas Bacho Kiro 1653 (35ka) from Bulgaria, Muierii 1 (34ka) and Cioclovina 1 (32ka) from Romania, and Paglicci 133 (33ka) from southern Italy are equally related to Goyet Q116-1 and Sunghir. Contrary to West Siberian hunter-gatherers, Tutkaul 1 does not carry an extra eastern Eurasian ancestry, but shows affinity to Iranian Neolithic farmers and some younger populations from Iran and the Turan region (Supplementary Data 2.L). Preistoria e Antropologia, Universit degli Studi di Siena, Siena, Italy, Stefano Ricci,Francesco Boschin&Annamaria Ronchitelli, Centro Studi sul Quaternario ODV, Sansepolcro, Italy, Institut National de Recherches Archologiques, Bertrange, Luxembourg, Department of Cultural Heritage, University of Bologna, Ravenna, Italy, Gregorio Oxilia,Eugenio Bortolini,Stefano Benazzi&Matteo Romandini, Human Ecology and Archaeology (HUMANE), Department of Archaeology and Anthropology, Instituci Mil i Fontanals de Investigacin en Humanidades, Consejo Superior de Investigaciones Cientficas (IMF - CSIC), Barcelona, Spain, UMR 7209Archozoologie et Archobotanique-Socits, Pratiques et Environnements, Musum National dHistoire Naturelle, Paris, France, Dipartimento di Scienze Della Vita e DellAmbiente, Sezione di Neuroscienze e Antropologia, Universit Degli Studi di Cagliari, Cittadella Monserrato, Cagliari, Italy, Dipartimento di Civilt e Forme Del Sapere, Universit di Pisa, Pisa, Italy, Center for Isotope Research, Groningen University, Groningen, The Netherlands, UMR 7206 co-Anthropologie, quipe ABBA. PLoS Biol. Currently use of the word 'vape' now means "to inhale and exhale the vapor produced by an . BMC Res. The Gravettian culture was one of the most widely distributed Upper Palaeolithic cultures across western Eurasia before the LGM19. performed or supervised laboratory work. Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. The tree was calculated on 16,528 positions (partial deletion 95%) and with 500 bootstrap iterations using MEGA1097. Chintalapati, M., Patterson, N. & Moorjani, P. The spatiotemporal patterns of major human admixture events during the European Holocene. Article In addition to this general data science content, Tina teaches SQL . Wyprodukowany w konwencji anime serial stanowi spin-off produkcji "Midzy nami, Misiami", ktrej reyserem wykonawczym . The f4-statistics were calculated by qpDstat 755 with parameter f4 mode: YES, with the Mbuti.DG population from Africa used as outgroup in all f-statistics analyses. Shes also the creator of the Microsoft Excel spreadsheet Data Mining 101. She has also published a book titled Data Science: Principles and Practices which she wrote with co-author Dan Ariely. The membrane was able to achieve FRR of 98.73 0.83 % after 4 cycles of filtration, indicating that anti-fouling properties have been enhanced. They were linked by a common archaeological culture: they used similar weapons and produced similar portable art. 537, 2432 (2020). Furthermore, the findings show that there had been no genetic exchange between contemporaneous hunter-gatherer populations in western and eastern Europe for more than 6,000 years. 5). Genet. Planning and Learning in Partially Observable Systems via Filter Stability Noah Golowich (MIT); Ankur Moitra (Math & CSAIL, MIT); Dhruv Rohatgi (MIT) New Subset Selection Algorithms for Low Rank Approximation: Offline and Online David P. Woodruff, Taisuke Yasuda (Carnegie Mellon University) Good Quantum LDPC Codes with Linear Time Decoders Irit Dinur (Weizmann); Min-Hsiu Hsieh (Hon Hai Quantum . To bind DNA, silica columns for high volumes (High Pure Viral Nucleic Acid Large Volume Kit (Roche)) were used. 2b). . Madrid, Madrid, Spain. @hellotinah. Illumina sequencing platforms were also used to sequence the 1240k and mtDNA captured libraries (Supplementary Data 1.B). Protoc. Enjoy maximum flexibility and forget about cramming against the clock. Meet Tina Huang. 1c and Extended Data Fig. The authors declare no competing interests. Both newly sequenced genomes from Solutrean-associated individuals (Le Piage II (23ka) from southwestern France and La Riera (level 14, 21ka) from northern Spain) show a generalized affinity with members of the Fournol and GoyetQ2 clusters in outgroup f3-statistics (Supplementary Data 2.A). 370. 1c). All Rights Reserved. Its mainly used in industries such as finance, insurance, healthcare, and insurance-related apps such as credit card applications, vehicle purchasing, etc. You also get a peek at Tina's Resume, so I don't think you want to miss out on that. Low latency, reasonably low communication overhead and ability to support real time applications are the reasons for . Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal. I'm I've learned SQL before, but I need a refresher. Other proposed climatic refugia for human survival during this period are the Italian peninsula, the Balkans and the southeastern European Plain, but the actual genetic contribution of populations from these regions to post-LGM Europeans is highly debated11,12,13. Genetics 192, 10651093 (2012). In addition to her rich experience, including bioinformatics cancer research at OICR, Tina is a . I hold a Bachelor's degree at the University of Toronto where I studied pharmacology. Tina Huang | Propel | Build Something Together Subsequently, I worked in . Check out my courses where we apply scientifically backed learning techniques to accomplish our goals. Details on individuals involved in the analysis, read counts processing and allele frequency computation are provided in the Supplementary Information, section12 and Supplementary Data 1.J and 3.G. Sci. under exclusive license to Springer Nature Singapore Pte Ltd. 2022 R. Huang et al. 864358 (to K.M. CONTACT US Contact us. Paradis, E., Claude, J. Nature 592, 253257 (2021). 1). Are you Tina Huang? of Leiden, 2000). . El Mirn has a significantly higher similarity to theVillabruna clusterthan Fournol 85 and Le Piage II, while the affinity to theVillabruna cluster in Le Piage II is not significantly higher than in Fournol 85 (Supplementary Data 2.D). Double-stranded DNA libraries were built from 25l of DNA extract, without the presence of uracil DNA glycosylase (ds_nonUDG) or in the presence of uracil DNA glycosylase (ds_halfUDG), following a double-stranded UDG-half library preparation to reduce, but not eliminate, the amount of deamination-induced damage towards the ends of ancient DNA (aDNA) fragments58. The MDS analysis showing the genetic affinity among European hunter-gatherers was based on the distance matrix derived from outgroup f3-statistics, in the form 1f3(Mbuti.DG; pop1, pop2) and performed with classical MDS algorithm (cmdscale) implemented in R 3.5.1. . This procedure allowed us to manually traverse the ISOGG Y-Haplogroup Tree, checking in a semi-automatic way which positions were covered. Nat. Lifetime access to all course materials and updates. Radiocarbon 62, 725757 (2020). Yu Ting Wang, Wen Lin Huang, Yan Ting Cheng. C.L.S. Last Name Huang #8. 7 Admixture dates between Oberkassel/Villabruna and ANE ancestries in the oldest individuals from the Sidelkino cluster. Between 14 and 8ka, all hunter-gatherers in western and central Europe carried only Oberkassel ancestry, with no detectable contribution from the Sidelkino cluster. Article 5 Summary of ROH segments detected in Eurasian hunter-gatherers. In general, the whole point of data warehousing is to get the data from your source to your target. Genomic and dietary discontinuities during the Mesolithic and Neolithic in Sicily. We were also told that her project was one of the first student projects that has been accepted into a top-tier universitys student programming competition. Peltzer, A. et al. 7 and Supplementary Table 3), which coincides roughly with the first appearance of the Oberkassel ancestry in central Europe. One of my favorite videos of her is where she talks about the resume that got her an entry-level data science job. Great content - Tina is all class and an excellent instructor. thua808@aucklanduni.ac.nz. Shes the founder of Coding Black Females, a nonprofit with the aim to provide opportunities for Black female developers to develop themselves, meet familiar faces, network, receive support, and build relationships through having regular meetups., Check out the Coding Black Females website. Lazaridis, I. et al. The admixture graph shows that the Bacho Kiro IUP group (n=3) shares ancestry with multiple early modern human lineages2 (Supplementary Information, section7), and that the more than 45,000-year-old Zlat k genome1 is the most deeply divergent non-African lineage sequenced to date (Extended Data Fig. Ancient Rome: A genetic crossroads of Europe and the Mediterranean. Lcuyer, C., Hillaire-Marcel, C., Burke, A., Julien, M. A. Furthermore, the gene pool of the western Gravettian populations is found continuously for at least 20,000 years: their descendants who are associated with the Solutrean and Magdalenian cultures stayed in southwestern Europe during the coldest period of the last Ice Age (between 25,000 and 19,000 years ago) and later spread north-eastward to the rest of Europe. The newly generated genotypes were merged with 240 published ancient hunter-gatherer genomes and modern worldwide populations for downstream analyses (Supplementary Data 1.G). CNRS, MNHN, Universit de Paris Cit, Muse de lHomme, Paris, France, PALEVOPRIM Lab UMR 7262 CNRS-INEE, University of Poitiers, Poitiers, France, Centre de Valorisation des Collections Scientifiques, Universit de Poitiers, Mignaloux Beauvoir, France, Muses de PoitiersVille de Poitiers, Poitiers, France, Departamento de Geologa, Facultad de Ciencia y Tecnologa, Universidad del Pas Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Leioa, Spain, Sociedad de Ciencias Aranzadi, Donostia-San Sebastian, Spain, Centro UCM-ISCIII de Investigacin sobre Evolucin y Comportamiento Humanos, Madrid, Spain, Institute of Archaeology, University of Rzeszw, Rzeszw, Poland, Foundation for Rzeszw Archaeological Centre, Rzeszw, Poland, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA, Department of Psychiatry, Harvard Medical School, Boston, MA, USA, Groninger Instituut voor Archeologie, Groningen University, Groningen, The Netherlands, Institute of Archaeology and Ethnology, Polish Academy of Science, Pozna, Poland, Institute of History, Archaeology and Ethnography, Dushanbe, Tajikistan, ArchaeoZOOlogy in Siberia and Central AsiaZooSCAn, CNRSIAET SB RAS International Research Laboratory, IRL 2013, Institute of Archaeology SB RAS, Novosibirsk, Russia, Research Institute and Museum of Anthropology, Moscow State University, Moscow, Russia, Grupo de I+D+i EVOADAPTA (Evolucin Humana y Adaptaciones durante la Prehistoria) Departamento de Ciencias Histricas, Universidad de Cantabria, Santander, Spain, Borja Gonzlez-Rabanal,Ana B. Marn-Arroyo&Lawrence G. Straus, Instituto Internacional de Investigaciones Prehistricas de Cantabria (IIIPC), Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain, Departamento de Biologa de Organismos y Sistemas, Universidad de Oviedo, Oviedo, Spain, Quaternary Environments and Humans, OD Earth and History of Life, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Caroline Polet,Ivan Jadin&Sbastien Villotte, Muses Royaux dArt et dHistoire, Bruxelles, Belgium, Institute of Historical Research, University of Girona, Catalonia, Spain, Joaquim Soler,Neus Coromina&Isaac Ruf, INRAP/UMR 8215 Trajectoires 21, Paris, France, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA, Department of Anthropology, University of New Mexico, Albuquerque, NM, USA, GoArchPal-GoArchon, Viville sous-les-Cotes, France, Archologie & Mnzkabinett, Universalmuseum Joanneum, Graz, Austria, Museum Das Dorf des Welan, Wllersdorf-Steinabrckl, Austria, Department of Humanities, University of Ferrara, Ferrara, Italy, National Museum of Antiquities, Leiden, The Netherlands, Faculty of Archaeology, Leiden University, Leiden, The Netherlands, Biogeology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Unit de Recherches Art, Archologie Patrimoine, Universit de Lige, Lige, Belgium, I.U. Using f4-statistics and qpAdm, we confirm that EHG populations in eastern Europe are a mixture of Villabruna/Oberkassel and ANE ancestries (Supplementary Information, section11 and Supplementary Data 2.K). Article 6 Reasons We Just Cant Stop. For consistency with the previously discussed nomenclature, we rename the EHG ancestryas the Sidelkino cluster(hereafter, Sidelkino cluster or ancestry). Late Upper Palaeolithic hunter-gatherers in the Central Mediterranean: new archaeological and genetic data from the Late Epigravettian burial Oriente C (Favignana, Sicily). The newly reported individuals with over 15,000 SNPs on the Human Origins dataset are shown in black-outlined and filled symbols, as illustrated in the legend on the right, while representative ancient genomes are shown in outlined symbols, as illustrated in the legend at the bottom of the PCA. The pre-40kagroup and theFournol and Vstonice clusters are marked as shaded areas in different colours. They, along with it, will be accessible to you indefinitely. Science 360, 548552 (2018). (2023, March 1). Its not just the top 200 that this competition attracts, but anyone interested in data science. Natl Acad. Yang, M. A. et al. Herein, methane is upgraded through the photocatalytic oxidative coupling of methane (OCM) over a ternary Ag-AgBr/TiO 2 catalyst in a pressurized flow reactor. Renaud, G., Slon, V., Duggan, A. T. & Kelso, J. Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA. Reducing microbial and human contamination in DNA extractions from ancient bones and teeth. If material is not included in the articles Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. 116, 105100 (2020). In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. Genome Res. Curr. The deduplicated bam files were filtered using PMDtools 0.6068 with a threshold of 3, to reduce potential modern DNA contamination based on postmortem DNA deamination. As a Graduate and Consultant in the Business Tax Advisory (Financial Services) team, I provided tax advice and tax compliance services to organisations in the banking and capital markets, wealth and . 1c) and a west Eurasian principal component analysis (PCA) (Extended Data Fig. use of cookies The ancestry found in individuals associated with the preceding Aurignacian culture from central Europe (GoyetQ116-1ancestry) gave rise to Gravettian-associated individuals from western and southwestern Europe. a,b, The ancestries of individuals in the GoyetQ-2 cluster and Iberian hunter-gatherers (HGs) (a) and individuals in the Oberkassel cluster (b) were modelled using qpAdm, with Fournol 85 and Arene Candide 16 representing the Fournol and Villabruna ancestries, respectively. Tina Huang. Great explanations and feels like real interviews that helps me warm up myself before the real interview! Mateja Hajdinjak, Fabrizio Mafessoni, Svante Pbo, D. M. Fernandes, D. Strapagiel, R. Pinhasi, Pavel Flegontov, N. Ezgi Altnk, Stephan Schiffels, Daniel M. Fernandes, Kendra A. Sirak, David Reich, Sandra Oliveira, Kathrin Ngele, Mark Stoneking, Eirini Skourtanioti, Harald Ringbauer, Philipp W. Stockhammer, Vanessa Villalba-Mouco, Marieke S. van de Loosdrecht, Wolfgang Haak, Joseph H. Marcus, Cosimo Posth, John Novembre, Natalija Kashuba, Emrah Krdk, Anders Gtherstrm, Nature Karmin, M. et al. Shes currently at Microsoft. We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe.